Eccrine hidradenoma is a rare benign cutaneous neoplasm, believed to arise from the distal excretory duct of the eccrine sweat glands [1]. Because a. Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. Another name for tumors that were previously believed to strictly derive from specific sweat gland types may, in fact, derive from both eccrine or apocrine glands. Hidradenoma is a cutaneous, often benign tumour of the sweat glands. Also known by various other names such as nodular hidradenoma, eccrine acrospiroma.

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This oncology article is a stub. Find articles by Chung Hun Kim. Because a consensus has not been reached regarding its histogenesis, eccrine hidradenoma is also known as nodular hidradenoma, clear cell hidradenoma, eccrine acrospiroma, and eccrine sweat gland adenoma.

Giant Eccrine Hidradenoma Mimicking a Malignant Tumor of the Salivary Gland

Report of seven cases. They may ulcerate or bleed.

Eccrine and apocrine naevi are rare malformations of the glandular component of an eccrine or apocrine gland. Clear cell eccrine carcinomas of the skin. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

The common sites hidradfnoma occurrence are scalp, face, anterior trunk and extremities. There is an association with cylindromas, and a genetic condition Brooke-Spiegler syndrome results in multiple spiradenomas, cylindromas and trichoblastomas.

Sweat gland lesions | DermNet NZ

They are classified by their histological features. During which it had gradually progressed in size over the years but showed rapid progression in size in the past 6 months.

Fine needle aspiration cytology FNAC and core needle biopsy were done but were inconclusive. Can’t read the image?


Sweat gland lesions

Although the exact mechanism of invasion by benign tumors has not yet been elucidated, benign tumor cells might invade into the deep structures along nerves such as the facial nerve and trigeminal nerve, as observed ecvrine this case. Scalp is a known and yet uncommon site of occurrence.

Variants of these lesions were previously called papillary adenoma or tubulopapillary carcinoma. December 29, Citation: In general, it is biphasic and is characterized by an admixture of polygonal epithelial and spindle-shaped myoepithelial elements in a background stroma.

Poromas are a group of benign growths of poroid differentiation, i. This cell mass showed two distinct cell populations. Treatment involves surgical excision of the entire lesion. Rook’s Textbook of Dermatology 8th ed. This article has been cited by other articles in PMC. The swelling was in the parietes and was freely mobile.

On Histopathological examination both solid and cystic components are present with characteristic clear cells, which contain a large amount of glycogen and thus appear clear under light microscopy. A eccrrine examination revealed a loss of forehead wrinkles, eyebrow ptosis, mild ectropion of the lower eyelid, and mild depression of the mouth corner on the right side of his face, which were consistent with facial nerve paralysis House-Brackman grade IV Fig.

Tumours of the Skin Appendages: Sccrine of the wide local excision of the tumour revealed benign nodular hidradenoma. The report may describe a circumscribed proliferation of compact cuboidal keratinocytes with small monomorphous nuclei and scant eosinophilic cytoplasm. He had difficulty opening his mouth and closing his right eyelid. Integumentary neoplasia Epidermal nevi, neoplasms, cysts Oncology stubs Epidermal nevi, neoplasm, cyst stubs.

The tumor is usually confined to the dermis or subcutaneous layer without involving the deep structures. Report of a case with fine needle aspiration cytology features and histologic correlation. One report explained the mechanism of metastasis of benign tumors: Because sweat gland naevi are harmless, usually no treatment is required, but some patients may prefer to have them removed surgically.


Discussion of sweat gland tumors can be difficult and confusing due to the complex classification and redundant terminology used to describe the same tumors. They present as papulesplaques or nodules and are diagnosed on biopsy. The main specimen from the preauricular area consisted of a nodular, rubbery, firm myxoid mass, measuring 8.

The tumor mass extended to the cranial base around the right foramen ovale without any intracranial extension black arrow. A 41 year old man presented with a painless ulcero-proliferative polypoidal swelling over the right lower anterior abdominal wall. Eccrine glands secrete a salty solutionwhich reaches the skin pores via an eccrine duct.

It appears as a solitary nodule lump or cyst when it is called cystic hidradenoma and may appear on any site. Open in a separate window. Computed tomography showed a large mass occupying the parotid space, the masticatory space, and the temporal region, with infiltrations into the temporalis muscle and pterygoid muscles.

They are not often identified clinically before biopsy. Am J Clin Pathol ; Suppl 1: Cancers derived hidradwnoma apocrine tissue are often described as adnexal carcinomas. It usually presents as a single, small skin-colored lesion, and is considered distinct from the closely related poroma.

They are typically found on the fingers, palms, toes or soles. Ultrasonography USG abdomen and pelvis was done to evaluate the presence of any intra-abdominal pathology, but was unremarkable. A rare naevus called porokeratotic eccrine ostial and dermal duct naevus is categorised within epidermal naevi.